{"id":20901,"date":"2026-02-23T07:33:31","date_gmt":"2026-02-23T07:33:31","guid":{"rendered":"https:\/\/mybrand.ee\/?page_id=20901"},"modified":"2026-02-23T16:23:19","modified_gmt":"2026-02-23T16:23:19","slug":"kuiva-nina-sundroom","status":"publish","type":"page","link":"https:\/\/mybrand.ee\/en\/kuiva-nina-sundroom\/","title":{"rendered":"Dry nose syndrome"},"content":{"rendered":"\t\t
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MIDA T\u00c4HENDAB HNPK?<\/h4>

Kuiva nina s\u00fcndroom ehk p\u00e4rilik nasaalne parakeratoos (HNPK[1]<\/a>) on nahahaigus, mis kahjustab koera ninapeeglit. Kergematel juhtudel tekib ninapeegli \u00e4\u00e4rde pisut kuiv ja krobeline riba, mis ei h\u00e4iri koera elu ja j\u00e4\u00e4b m\u00f5nikord ka inimesele m\u00e4rkamata. Raskematel juhtudel tekivad nina sisse s\u00fcgavad l\u00f5hed ja veritsevad praod, mis vajavad ravi. On ka juhtumeid, kus kogu nina ja seda \u00fcmbritsevad limaskestad v\u00f5ivad depigmenteeruda.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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T\u00e4ielikult depigmenteerunud nina. Foto My Brand Labradors.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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KELLEL SEDA ESINEB?<\/h4>

Haigus esineb labradori retriiveritel v\u00f5i nendest p\u00f5lvnevatel segaverelistel koertel (labradoodle, labradoride ja kuldsete segud jne[2]<\/a>). Haigus ilmneb alles suguk\u00fcpseks saades, enamasti 6-12 kuu vanuses ja ilmneb m\u00f5lemast soost koertel. Samuti pole haigus seotud \u00fchegi v\u00e4rviga, seda v\u00f5ib esineda nii mustadel, pruunidel kui kollastel labradoride. Haigus ei ole eluohtlik, ei p\u00f5hjusta koerale muid vaevusi ja v\u00f5ib \u00f5nne korral t\u00e4hendada vaid esteetilist probleemi.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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L\u00f5hedega nina enne ravi. Foto My Brand Labradors.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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KUIDAS TEADA, KAS MU KOERAL ON SEE?<\/h4>

Kuigi kuivadest ninadest on kasvatajad kuulnud aastaid, ei ole HNPK diagnoosimine olnud lihtne \u00fclesanne ja seda ei tunta ka t\u00e4nap\u00e4eval iga kord \u00e4ra. Aastate jooksul on esitatud versioone, et koer p\u00f5letas nina vastu kuuma grilli \u00e4ra v\u00f5i armastab kaevata ja ninaga maad k\u00fcnda, tal on p\u00e4ikeseallergia v\u00f5i luupus.<\/p>

Haiguse nimetus ja kirjeldus ilmus kirjandusse alles alates 2000-ndate l\u00f5pus ja esimesena tuli tasulise geenitestiga v\u00e4lja Genoscoperi labor Soomes. T\u00e4naseks pakuvad patendi alusel HNPK testi mimtmed laborid \u00fcle maailma ja testimine on j\u00f5udnud viimaste aastate jooksul populaarseks saada ka \u00fcle ookeani. Esialgsetel andmetel kannab HNPK geeni umbes 10% labradori retriiveritest, kes ise on siis vastavalt kas haiguse kandjad v\u00f5i p\u00f5dejad[3]<\/a>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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HNPK testimine on lihtne ja k\u00e4ttesaadav k\u00f5igile ka kodustes tingimustes. Testimiseks v\u00f5etakse koera p\u00f5sest vatipulgaga proov ja saadetakse \u00fcmbrikus laborisse. Proovi v\u00f5tmine on koerale valutu ja ei vaja narkoosi v\u00f5i tuimestust. Testi vastus annab tulemuseks \u00fche j\u00e4rgmistest variantidest:\u00a0Normal<\/strong>\u00a0(puhas, mutatsiooniga geeni ei leidu),\u00a0Carrier<\/strong>\u00a0(kandja, omab mutatsiooniga geeni) v\u00f5i\u00a0Affected<\/strong>\u00a0(haige, omab kahte mutatsiooniga geeni).<\/p>

HNPK-d p\u00f5hjustab geenimutatsioon SUV39H2 geenis[4]<\/a>. Haigus p\u00e4randumisviis on monogeneetiliselt autosomaalne retsessiivne, mis t\u00e4hendab, et haiguse ilmnemiseks on vaja saada m\u00f5lemalt vanemalt mutatsiooniga geen. Ehk kui koer on saanud kuiva nina s\u00fcndroomi, siis peavad m\u00f5lemad ta vanemad olema v\u00e4hemalt haiguse kandjad.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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KUIDAS RAVIDA?<\/h4>

Haiguse ravimine t\u00e4hendab ennek\u00f5ike ninapeegli niisutamist ja vajadusel antibiootiliste salvide kasutamist. Kasvatajate foorumites jagatakse edukaid kogemusi E-vitamiinirikka toitumiskava ning looduslike salvide v\u00f5i h\u00fcgieeniliste huulepulkade kasutamise kohta.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Sama nina peale \u00fchekuulist ravi toidulisandite ja h\u00fcgieenilise huulepulgaga. Foto My Brand Labradors.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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KAS KUIVA NINAGA KOERI TOHIB ARETUSES KASUTADA?<\/h4>

Allpool on tabel, mis illustreerib HNPK p\u00e4randumismehhanismi:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Kuna kaks mutatsiooniga geeni v\u00f5ivad toota tulemuseks j\u00e4rglase, kes haiguse all kannatab, siis soovitatakse tungivalt paaritada mutatsiooni kandjaid vaid koertega, kelle testi tulemus on puhas, et v\u00e4ltida haigete kutsikate s\u00fcndi.<\/p>

[1]<\/a>\u00a0Hereditial Nasal Parakeratosis (ingl.k<\/em>)<\/p>

[2]<\/a>\u00a0Optigen\u00a0http:\/\/www.optigen.com\/opt9_hnpk_test.html<\/a><\/p>

[3]<\/a>\u00a0Vt eelmist<\/p>

[4]<\/a>\u00a0Jagannathan et al., (2013) A Mutation in the SUV39H2 Gene in Labrador Retrievers with Hereditary Nasal Parakeratosis (HNPK) Provides Insights into the Epigenetics of Keratinocyte Differentiation. PLOS Genetics, 9, e100384.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

MIDA T\u00c4HENDAB HNPK? Kuiva nina s\u00fcndroom ehk p\u00e4rilik nasaalne parakeratoos (HNPK[1]) on nahahaigus, mis kahjustab koera ninapeeglit. Kergematel juhtudel tekib ninapeegli \u00e4\u00e4rde pisut kuiv ja krobeline riba, mis ei h\u00e4iri…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-20901","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mybrand.ee\/en\/wp-json\/wp\/v2\/pages\/20901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mybrand.ee\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mybrand.ee\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mybrand.ee\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mybrand.ee\/en\/wp-json\/wp\/v2\/comments?post=20901"}],"version-history":[{"count":5,"href":"https:\/\/mybrand.ee\/en\/wp-json\/wp\/v2\/pages\/20901\/revisions"}],"predecessor-version":[{"id":21125,"href":"https:\/\/mybrand.ee\/en\/wp-json\/wp\/v2\/pages\/20901\/revisions\/21125"}],"wp:attachment":[{"href":"https:\/\/mybrand.ee\/en\/wp-json\/wp\/v2\/media?parent=20901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}